Information from EmeraMed2026-10-06T04:00:39-05:00

What a 2012 Rat Study Found About NBMI After Lethal Mercury Doses

In a 2012 peer-reviewed rat study, every untreated rat given a lethal dose of mercury chloride died, while 16 of 18 rats given a single injection of investigational NBMI (Emeramide) survived the full week, including 4 of 6 at 14 times the lowest lethal dose. The survivors stayed healthy and active through three months of follow-up. Preclinical animal data only; NBMI is not FDA-approved.

How Emeramide (NBMI) Changed Mercury Signaling in Cultured Endothelial Cells

In this 2011 laboratory study, researchers grew mouse blood-vessel lining cells in dishes and exposed them to mercury. The mercury made a cell-signaling process called phospholipase D more active, lowered the cells’ protective glutathione levels, and increased signs of cell stress. When they added Emeramide (also called NBMI) to the same cultures, those mercury-related changes were smaller: PLD activity dropped, glutathione moved back toward normal, and stress markers were lower.

Seeking Partners in Development

EmeraMed is seeking strategic partners and investors to support the continued clinical development and potential commercialization of Emeramide (also known as NBMI or Irminix®). Emeramide is designed to bind irreversibly to certain heavy metals (such as mercury, arsenic, cadmium, lead, and others) and to address oxidative stress.

Clinical Trials

The most current, up-to-date information on our clinical trials.

Pilot Study Results: Emeramide (NBMI) in Mercury-Exposed Gold Miners in Zaruma Ecuador

In a 2018 randomized, placebo-controlled pilot study of 36 mercury-exposed gold miners in Zaruma, Ecuador, the group taking 300 mg/day of investigational NBMI (Emeramide) showed a statistically significant drop in physical fatigue scores and significantly lower urinary mercury (unadjusted) compared with placebo after 14 days. No serious adverse events were reported. NBMI is not FDA-approved.

Discover The Future of Health

We are committed to advancing the development of Emeramide (also known as Irminix®), a lipophilic di-thiol compound, with a focus on toxicology-related conditions.

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